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184. 185. 186. 187. 188. 189. 190. 191. 192. 193. 194. 195. 196. 197. 198. 199. 200. 201. 202. 203. 204. 205. , Teslova 30, 1000 Ljubljana, Slovenia Boehringer Ingelheim Austria GmbH, Dr. Boehringer Gasse 5–11, 1121 Vienna, Austria Monolithic supports represent a novel type of stationary phases for liquid and gas chromatography, for capillary electrochromatography, and as supports for bioconversion and solid phase synthesis. As opposed to individual particles packed into chromatographic columns, monolithic supports are cast as continuous homogeneous phases.

Boehringer Gasse 5–11, 1121 Vienna, Austria Monolithic supports represent a novel type of stationary phases for liquid and gas chromatography, for capillary electrochromatography, and as supports for bioconversion and solid phase synthesis. As opposed to individual particles packed into chromatographic columns, monolithic supports are cast as continuous homogeneous phases. They represent an approach that provides high rates of mass transfer at lower pressure drops as well as high efficiencies even at elevated flow rates.

51 52 53 54 55 55 Advances in Biochemical Engineering/ Biotechnology, Vol. 76 Managing Editor: Th. Scheper © Springer-Verlag Berlin Heidelberg 2002 50 A. Strancar et al. 3 Preparation of SMC and Scale-Up Strategies . . . . . . 2 Synthesis of the SMC . . . . . . . . . . . . . 62 Preparation of Large Scale SMC . . . . . . . . . . 63 4 Characteristics and Application of SMC in the Liquid Chromatography of Biomolecules . . . . . . . . . 1 Characteristics of the SMC .

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