Download Cannabinoids and the brain by Attila Köfalvi PDF

By Attila Köfalvi

Endocannabinoids have large healing strength. This ebook introduces readers to our present realizing of the neurobiology of endocannabinoids and comparable structures, detailing their pathophysiological function and healing strength. Authors, skilled medical investigators, current and study result of contemporary scientific trials in addition to the advance of recent healing innovations and medicines.

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Sugiura T, Yoshinaga N, Waku K (2001) Rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain after decapitation. Neurosci Lett 297:175–178. Sugiura T, Kishimoto S, Oka S, Gokoh M (2006a) Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. Prog Lipid Res 45:405–446. Sugiura T, Oka S, Ikeda S, Waku K (2006b) Occurrence, biosynthesis, and metabolism of endocannabinoid. In: Onaivi ES, Sugiura T, Di Marzo V (eds), Endocannabinoids: The Brain and Body’s Marijuana and Beyond.

A 31P NMR and enzyme activity study. J Lipid Res 41:985–990. Moesgaard B, Petersen G, Mortensen SA, Hansen HS (2002) Substantial species differences in relation to formation and degradation of N-acyl-ethanolamine phospholipids in heart tissue: an enzyme activity study. Comp Biochem Physiol B, Biochem Mol Biol 131:475–482. Morishita J, Okamoto Y, Tsuboi K, Ueno M, Sakamoto H, Maekawa N, Ueda N (2005) Regional distribution and age-dependent expression of N-acylphosphatidylethanolamine-hydrolyzing phospholipase D in rat brain.

Di Marzo V, Fontana A, Cadas H, Schinelli S, Cimino G, Schwartz JC, Piomelli D (1994) Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372:686–691. Di Marzo V, De Petrocellis L, Sepe N, Buono A (1996a) Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. Biochem J 316:977–984. Di Marzo V, De Petrocellis L, Sugiura T, Waku K (1996b) Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells.

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