By Sebastian Seung
We all know that every people is exclusive, yet technological know-how has struggled to pinpoint the place, accurately, our distinctiveness is living. Is it in our genes? The constitution of our brains? Our genome might confirm our eye colour or even elements of our character. yet our friendships, disasters, and passions additionally form who we're. The query is: how?
Sebastian Seung, a dynamic professor at MIT, is on a quest to find the organic foundation of id. He believes it lies within the development of connections among the brain's neurons, which switch slowly over the years as we research and develop. The connectome, as it's referred to as, is the place our genetic inheritance intersects with our lifestyles event. It's the place nature meets nurture.
Seung introduces us to the devoted researchers who're mapping the brain's connections, neuron by way of neuron, synapse through synapse. it's a enormous undertaking—the medical an identical of mountain climbing Mount Everest—but in the event that they be successful, it may possibly exhibit the root of character, intelligence, reminiscence, and even perhaps psychological issues. Many scientists speculate that folks with anorexia, autism, and schizophrenia are "wired differently," yet not anyone understands needless to say. The brain's wiring hasn't ever been essentially seen.
In sparklingly transparent prose, Seung unearths the superb technological advances that may quickly aid us map connectomes. He additionally examines the facts that those maps will sometime let people to "upload" their minds into pcs, reaching one of those immortality.
Connectome is a mind-bending event tale, instructed with nice ardour and authority. It offers a bold clinical and technological imaginative and prescient for eventually knowing what makes us who we're. Welcome to the way forward for neuroscience.
Read Online or Download Connectome: How the Brain's Wiring Makes Us Who We Are PDF
Best neuroscience books
Experimental philosophy is a brand new flow that seeks to come the self-discipline of philosophy to a spotlight on questions on how humans truly imagine and consider. Departing from a long-standing culture, experimental philosophers exit and behavior systematic experiments to arrive a greater figuring out of people's traditional intuitions approximately philosophically major questions.
The fellow Who Mistook His spouse for a Hat brings jointly twenty-four of Oliver Sacks’ so much attention-grabbing and cherished case stories. The sufferers in those pages are faced with nearly inconceivably unusual neurological problems; in Sacks’ telling, their tales are a profound testomony to the adaptability of the human mind and the resilience of the human spirit.
A accomplished, multidisciplinary evaluate, Neural Plasticity and reminiscence: From Genes to mind Imaging presents an in-depth, updated research of the examine of the neurobiology of reminiscence. major experts proportion their clinical adventure within the box, protecting a variety of themes the place molecular, genetic, behavioral, and mind imaging strategies were used to enquire how mobile and mind circuits can be transformed by way of adventure.
Encephalitis Lethargica: in the course of and After the Epidemic is resembling a detective novel a few significant scientific secret that is still unsolved. throughout the Twenties and Nineteen Thirties a wierd, very polymorphic affected a lot of the area even if no longer while in every single place and positively now not with a similar signs.
- Le cervelet: De l’anatomie et la physiologie `la clinique humaine
- Exploring the Vertebrate Central Cholinergic Nervous System
- Neural Regeneration
- INTERNATIONAL REVIEW NEUROBIOLOGY V 6, Volume 6 (v. 6)
- Neurology : PreTest self-assessment and review
Additional info for Connectome: How the Brain's Wiring Makes Us Who We Are
Amarenco PBJ et al. (1999). Effect of atovastatin compared with placebo on cerebrovascular endpoints in patients with previous stroke or transient ischemic attack: the SPARCL study. 8th European Stroke Conference, Venice, Italy. Anderson C. (2003). Blood pressure-lowering for secondary prevention of stroke: ACE inhibition is the key, Stroke 34:1333-1334. Antiplatelet Trialists’ Collaboration. (1994). Collaborative overview of randomised trials of antiplatelet therapy: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients, BMJ 308:81-106.
Hemorrhagic transformation in acute ischemic stroke: potential contributing factors in the European Cooperative Acute Stroke Study, Stroke 28:957-960. Lesage AS et al. (1996). Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway, J Pharmacol Exp Ther 279:759-766. Lewington S et al. (2002). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies, Lancet 360: 1903-1913.
1 Mechanisms of action of ACE inhibitors and angiotensin II receptor subtype 1 blockers. ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker. particular classes of antihypertensive agents (Anderson, 2003; Bath, 2003; Davis and Donnan, 2003). The Heart Outcomes Prevention Evaluation (HOPE) (The Heart Outcomes Prevention Evaluation Study Investigators, 2000) was a double-blind, randomized, placebo-controlled trial of the use of an ACE inhibitor, ramipril, for the prevention of the composite outcome of MI, stroke, and cardiovascular death in high-risk cardiovascular disease patients.