Download Emergency drug dosing in children : a resuscitation aid for by Mike Wells; Lara Goldstein; Martin J Botha PDF

By Mike Wells; Lara Goldstein; Martin J Botha

Tips to use this booklet -- Overcoming drugs mistakes in paediatric emergencies -- management, teamwork, and resuscitation aids -- functional pharmacology in paediatric emergencies -- Emergency bolus drug dosing charts -- Emergency infusions dosing charts -- Drug dosing guidance : pearls and pitfalls -- gear guidance : pearls and pitfalls -- valuable formulation and data for dealing with paediatric emergencies

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Extra resources for Emergency drug dosing in children : a resuscitation aid for paediatric emergencies

Example text

Children of 2 to 6 years of age appear to clear drugs more rapidly than other developmental ages. Higher doses and shorter dosing intervals or higher infusion rates may be required in this group. Critical illness  Critically ill children often have renal dysfunction. The doses of drugs that are excreted via the kidneys should therefore be reduced for subsequent doses.  Hepatic dysfunction should also be taken into account. Enzymes for Phase I and II reactions will be hindered in their functioning, leading to a decreased metabolism of certain drugs as well as decreased perfusion of the liver, which again affects subsequent doses rather than the initial one.

1mg/mL) Amiodarone 5mg/kg 10 150mg/3mL + 7mL dil. 5mg/1mL + 4mL dil. 5mg/1mL + 4mL dil. 1mg/mL) 1 10 5mg/1mL + 9mL dil. 1mg/kg 10 1g/10mL undiluted (100mg/mL) 1 10 10mg/1mL + 9mL dil. 02mg/kg 1 10 1mg/1mL + 9mL dil. 1mg/mL) Cryoprecipitate 3mL/kg Cardioversion 1J/kg Adjust dose to indication; warm before use Defibrillation 4J/kg Joules - use the closest higher setting to the indicated energy level if this exact setting is not available. This may vary from machine to machine. Dantrolene 1mg/kg 60 20mg in 60mL dil.

5mg/mL) Phenytoin 20mg/kg Platelets 10mL/kg Adjust dose to indication; warm before use Potassium IV/IO for severe hypokalaemia Pralidoxime 25mg/kg 1 KCl 15% (2mmol/mL) - give SLOWLY 20 1g in 20mL dil. 5mg/kg 1 10 25mg/1mL + 9mL dil. 05mg/kg Ranitidine 1mg/kg Rehydration – mild dehydration 5 1% solution undiluted (10mg/mL) 10 1mg/1mL + 9mL dil. 1mg/mL) 1 10 50mg/2mL + 8mL dil. (5mg/mL) mL/hr for 24hours Rehydration – moderate dehydration mL/hr for 24hours Rehydration – severe dehydration mL/hr for 24hours Rocuronium 1mg/kg 1 10 50mg/5mL + 5mL dil.

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