By Tatiana Da Ros (auth.), Dr. Prof. Franco Cataldo, Dr. Tatiana Da Ros (eds.)
Medicinal Chemistry and Pharmacological power of Fullerenes and Carbon Nanotubes positive factors very important insights into the functions of fullerenes and carbon nanotubes. It discusses the fullerene and nanotubes derivatives that are powerful opposed to viruses, cells, and micro organism and people that are capable of engage and inhibit definite enzymes. additionally coated during this ebook are the formation of complicated constructions among biologically lively molecules and carbon fabrics. in addition, the applying of fullerenes in yes clinical treatments is explored, together with the very contemporary discovery of recent bio-compatible media that can be used as vendors within the supply of fullerenes in vivo. an extra subject of this article is the formation of hybrids among nanotubes and organic molecules and their use as chemical sensors.
Medicinal Chemistry and Pharmacological power of Fullerenes and Carbon Nanotubes can be a useful gizmo of reference for researchers, postgraduates and complicated undergraduates within the Chemical, Biomedical, and fabrics sciences.
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Additional info for Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes
2005), Patolsky et al. (2004); (f) Nguyen et al. (2002), Baker et al. (2002), Hazani et al. (2003), Li et al. (2005), Taft et al. (2004) O O (DNA) O 30 A. Bianco et al. 2 Biomedical Applications of Functionalised Carbon Nanotubes 31 Great effort has been made to overcome the barriers of CNTs towards bioapplications, especially those concerning the aqueous dispersion and biocompatibility. As a consequence the number of reactions that involve chemical modification of the tubes is progressively increasing.
3: 843–846. Chen J, Dyer MJ, Yu MF (2001a) Cyclodextrin-mediated soft cutting of single-walled carbon nanotubes. J. Am. Chem. Soc. 123: 6201–6202. Chen RJ, Zhang YG, Wang DW, Dai HJ (2001b) Noncovalent sidewall functionalization of singlewalled carbon nanotubes for protein immobilization. J. Am. Chem. Soc. 123: 3838–3839. Chen RJ, Bangsaruntip S, Drouvalakis KA, Kam NWS, Shim M, Li YM, Kim W, Utz PJ, Dai HJ (2003) Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors.
In these studies changes in the electronic levels in the nucleotide bases of the DNA molecule were found and the DNA acquired a chaotic spherical conformation upon interaction with CNTs. π–π interactions between the CNT sidewalls and the nucleic acid bases have been proposed as the mechanistic basis for this wrapping effect. , 2003a) and has been utilised to disperse CNT in solvents of varying polarity. , 2004; Rajendra and Rodger, 2005). An alternative functionalisation reaction described by Georgakilas et al.