By Chris G. McMahon (auth.), Emmanuele A. Jannini, Chris G. McMahon, Marcel D. Waldinger (eds.)
Premature ejaculation (PE) is a typical male sexual criticism, with a self-reported incidence of 20–30% in observational reviews. over the last 10–20 years, our figuring out of PE has advanced from the preliminary premise that it's a mental ailment to the present acceptance of an underlying organic and doubtless genetic predisposition in lots of instances. This new realizing has been followed through novel ways to the evaluation and therapy of sufferers with PE.
Premature Ejaculation is the 1st actually modern reference quantity at the topic. It covers a wide diversity of features suitable to PE, together with earlier and present definitions of the , the etiology of PE, its epidemiology, the influence of PE on either the sufferer and his associate, and the remedy of PE utilizing pharmacotherapy and/or psychotherapy/cognitive behavioral treatment. The e-book is definitely illustrated and referenced, and the first concentration all through is on evidence-based drugs.
This well timed and authoritative quantity might be of serious worth to sexual overall healthiness physicians, andrologists, endocrinologists, urologists, psychiatrists, sexologists, psychologists, and different healthcare professionals.
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Extra info for Premature Ejaculation: From Etiology to Diagnosis and Treatment
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Arendash GW, Gorski RA (1983) Effects of discrete lesions of the sexually dimorphic nucleus of the preoptic area or other medial preoptic regions on the sexual behavior of male rats. Brain Res Bull 10:147–154 6. Arnow BA, Desmond JE, Banner LL, Glover GH, Solomon A, Polan ML, Lue TF, Atlas SW (2002) Brain activation and sexual arousal in healthy, heterosexual males. Brain 125:1014–1023 7. Bancila M, Verge D, Rampin O, Backstrom JR, Sanders-Bush E, McKenna KE, Marson L, Calas A, Giuliano F (1999) 5-Hydroxytryptamine2C receptors on spinal neurons controlling penile erection in the rat.
At the time of ejaculation, the strongest activation was found in the mesodiencephalic transition zone including ventral tegmental area (VTA), SPFp, medial and ventral thalamus. Those thalamic areas are known to be associated with rewarding processes, visceral sensory responses, and control of pelvic floor motoneurons and sympathetic preganglionic neurons throughout the spinal cord. Notably, the VTA contains an A10 dopaminergic cell group belonging to the mesolimbic system and has previously been shown to be activated in humans during a cocaine or heroin rush [14, 88].