By Per Andersen, Richard Morris, David Amaral, Tim Bliss, John O'Keefe
The hippocampus is one among a gaggle of exceptional constructions embedded in the brain's medial temporal lobe. lengthy identified to be very important for reminiscence, it's been a primary concentration of neuroscience examine for a few years. The Hippocampus booklet supplies to facilitate advancements within the box in a huge means by means of bringing jointly, for the 1st time, contributions via best overseas scientists acquainted with hippocampal anatomy, body structure, and serve as. This authoritative quantity deals the main accomplished, updated account of what the hippocampus does, the way it does it, and what occurs while issues get it wrong. even as, it illustrates how study targeting this unmarried mind constitution has printed rules of wider generality for the total mind in terms of anatomical connectivity, synaptic plasticity, cognition and behaviour, and computational algorithms. Well-organized in its presentation of either concept and experimental information, this peerless paintings vividly illustrates the astounding growth that has been made in unraveling the workings of the mind. The Hippocampus booklet is destined to take a primary position on each neuroscientist's bookshelf.
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Extra info for The Hippocampus Book (Oxford Neuroscience Series)
The early studies exploited the fact that degenerating ﬁbers could be stained better than intact ﬁbers. Temporal myelinization gradients were also useful. Unfortunately, these methods initially met with limited success in the hippocampus. , 2002). These features are probably one reason why the ﬁrst available methods for experimentally establishing pathways by degenerating ﬁbers did not give satisfactory results. For example, even after appropriate lesions, Vittorio Marchi’s original method (Marchi and Algeri, 1886) stains only a small number of degenerating ﬁbers in the alveus and ﬁmbria.
With other cortical inﬂuences” (p. 206). Among other negative evidence, Brodal cited several studies that attested to the fact that the hippocampal formation was present in anosmatic and microsmatic animals such as dolphins and whales (Ries and Langworthy, 1937) and that there was substantial regional differentiation in microsmatic humans. Furthermore, he cited the data of William F. Allen (1940) in which lesions of the temporal lobe had no effect on the ability of dogs to perform olfactory discrimination tasks.
Endre Grastyán and colleagues (1959) proposed that theta activity could be coupled to speciﬁc learning states (Fig. 2–13). Both hippocampal and entorhinal theta waves showed distinct changes during the acquisition of conditioned response (Holmes and Adey, 1960). , 1949; Sloan and Jasper, 1950). Such responses were taken as evidence of a general activation of attention. , 1953). The reaction was associated with enhanced respiration and blood pressure. Similar reactions were elicited from the anterior cingulate gyrus, later to be associated with higher analysis of emotional signals.